Conducting a literature review is typically an iterative process. The following questions may help you to reflect on your experience and determine if you should improve and repeat your search.
How many citations were found?
How many databases were searched?
What terms were used to search for animal testing alternatives?
What period of time in the literature was searched?
Are the search terms used relevant to protocols in the study?
Are the search terms used appropriate for the databases that were searched?
According to 9 CFR 2.31 (d)(1)(ii) of the Animal Welfare Act, the researcher must have "considered alternatives to procedures that may cause more than momentary or slight pain or distress to the animals, and has provided a written narrative description of the methods and sources, e. g., the Animal Welfare Information Center, used to determine that alternatives were not available."
This narrative summary of the researcher's alternative search should at least include the following elements to convey a reasonable effort was made to determine the availability and practicality of alternative methods: